Santa Cruz Biotechnology offers conjugated and unconjugated monoclonal primary antibodies directed against most proteins involved in transcription regulation. To maintain homeostasis and to appropriately adapt to various changes, the cell must constantly produce the necessary gene products. Signal cascades transmit molecular messages leading to transcription factor activation and nuclear localization. Transcription factors bind to sequence-specific regions of DNA where they may act to promote or repress gene expression.
Most of our popular antibodies are also available as ImmunoCruz® Conjugates, including AC, HRP, PE, FITC, Alexa Fluor® 488, 546, 594, 647, 680, and 790 conjugates for direct Western Blotting and Staining applications, eliminating the need for a secondary antibody. Additional conjugates are also available for many antibodies, including Biotin, TRITC, PE-Cy5, PE-Cy7, APC, APC-Cy7, Alexa Fluor® 405, PerCP and PerCP-Cy5.5.
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